Clarification of Crystal Structure of Protein That “Removes” Causative Substance of Alzheimer’s Disease (Press Release)
- Release Date
- 03 Feb, 2015
- BL44XU (Macromolecular Assemblies)
Osaka University
A research group led by Junichi Takagi (professor) of the Institute for Protein Research, Osaka University, clarified the crystal structure of a protein that “removes” a causative substance of Alzheimer’s disease. In many neurodegenerative diseases such as Alzheimer’s disease, fibrillar aggregates called amyloid fibers generated in the brain destroy nerve cells, leading to brain dysfunction. Because the aggregates are accumulated in the brain over a long period, it is difficult to remove such aggregates once accumulation has started. A treatment method that prevents the accumulation of aggregates is considered necessary. |
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