X-ray phase contrast can reduce CT dose by more than two orders of magnitude

Release Date: 11 Dec, 2017

BL20B2 (Medical and Imaging I)

December 11, 2017
Monash University
Japan Synchrotron Radiation Research Institute (JASRI)

【 Key points 】
・The ability to improve CT image quality, or to reduce radiation exposure by factors in the hundreds to thousands, would have a dramatic impact for clinical diagnostics.
・Using less radiation will enable higher throughput imaging with fewer motion artefacts and be safer for human imaging or for longitudinal preclinical studies.

Senior research fellow Marcus Kitchen from Monash University in Australia and Chief Scientist Kentaro Uesugi, Eminent Scientist Naoto Yagi from Japan Synchrotron Radiation Research Institute, and researchers of University of Melbourne, New England University, and the Hudson Medical Research Institute have found at BL20B2 in SPring-8 that the radiation dose in medical imaging can be reduced by two orders of magnitude or more with the imaging method that utilizes refraction of X-rays. This research was conducted in a part of the beam time allocated to the long-term proposal of Professor Stuart Hooper from Hudson Medical Research Institute.

This research result was published online on "Scientific Reports" on 21st November 2017.

The full article can be read here.
The press release from Monash University can be read here.

Reference
Journal： Scientific Reports
Title of original paper：ＣＴ dose reduction factors in the thousands using X-ray phase contrast
Authors：Marcus J. Kitchen¹, Genevieve A. Buckley¹, Timur E. Gureyev^2,3,1, Megan J. Wallace^4,1, Nico Andres-Thio², Kentaro Uesugi⁵, Naoto Yagi⁵ & Stuart B. Hooper⁴
Affiliations：1 Monash University, Melbourne, Australia. 2 University of Melbourne, Melbourne, Australia. 3 University of New England, Armidale, Australia. 4 Hudson Institute for Medical Research, Melbourne, Australia. 5 Japan Synchrotron Radiation Research Institute, Japan.
doi：10.1038/s41598-017-16264-x

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X-ray phase contrast can reduce CT dose by more than two orders of magnitude