SPring-8, the large synchrotron radiation facility

Date&Time: 13:00-13:40, 19 April 2004

Speaker: Dr. Duncan McRee
Affiliation: President Active Sight and Adjunct Professor, the Scripps Research Institute

Abstract
　　While high throughput structural proteomics studies of bacterial proteins has proven to be possible, mammaliantargets have proven a lot more difficult for several reasons. The talk will present an example using P450 and show how we use the methods of high throughput structural proteomics to make many simultaneous attempts on a target to speed up the process of determining the structures of difficult protein targets.