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SPring-8 Users Community (SPRUC)


Research Group:

Study group for structural analysis of skin stratum corneum and hair for the development of cosmetics and pharmaceuticals

Contact:

Nakazawa Hiromitsu
1-155 Uegahara Ichiban-cho, Nishinomiya, Hyogo 662-8501, Japan
Telephone: +81-79-565-8093
nakazawa (at) kwansei.ac.jp

Research Area:

Life Science, Measurements

Beamline:

BL40B2ABL40XUABL43IRABL03XU

Overview of Research Group, Goals and Purposes:

The main interest of this research group is the analysis of interactions between formulation components and cosmetics and biological tissues such as the skin stratum corneum and hair, which are important in the formulation design of transdermal/topical formulation and cosmetics. The aim is to revitalize synchrotron radiation research in this field by collaborating with related researchers and widely sharing information, and to evolve and develop this research worldwide. The use of synchrotron radiation is essential for structural analysis of biological samples with low crystallinity, such as the stratum corneum, and for clarifying minute structural changes in the skin surface due to the penetration of substances such as solutions. It is difficult to carry out this research without synchrotron radiation. Therefore, related researchers from industry, government, and academia collaborate to collect various requests for synchrotron experiments that can serve as the basis for research related to skin-applied preparations, call for new users, and stably provide experimental opportunities. In addition, we will broadly discuss the current state of the research area, its technical problems, future expansion potential, and the development of new measurement methodologies, etc., and will summarize the content and make recommendations for synchrotron radiation facilities such as SPring-8. By making recommendations, we aim to contribute to the future development of synchrotron radiation research.
Keywords: Transdermal/topical formulation, cosmetics, stratum corneum, hair, small and wide-angle simultaneous scattering, infrared spectroscopy



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